Researchers from the Center for Excellence in Molecular Plant Sciences and collaborators have resolved for the first time the high-resolution crystal structure of the complex formed between the NodD protein of pea rhizobia and a flavonoid compound (hesperetin). They elucidated how NodD recognizes flavonoids and revealed key structural elements in NodD that determine the specificity of signal recognition.
A recent study led by Prof. ZHANG Xiaoming's team at the Institute of Zoology of the Chinese Academy of Sciences (CAS), in collaboration with Prof. Ian T. Baldwin's group at the CAS Center for Excellence in Molecular Plant Sciences, has uncovered a novel ecological strategy. Rather than passively "hitchhiking" within insect vectors, rice viruses actively manipulate plant defense pathways to protect their insect carriers.
Prof. GAO Ying's team from the Shanghai Institute of Nutrition and Health of the Chinese Academy of Sciences, along with collaborators from Hainan Medical University and Peking University Health Science Center, estimated the prevalence of hysterectomy of Chinese women, and revealed its association with metabolic disorders.
A research team from the Kunming Institute of Zoology has demonstrated for the first time in non-human primates that auditory stimulation at 40-Hz significantly elevates β-amyloid levels in the cerebrospinal fluid of aged rhesus monkeys, with this effect persisting for over five weeks.
A study led by ZHU Yingjie from the Shenzhen Institute of Advanced Technology of the Chinese Academy of Sciences discovered that activating the lateral septum (LS) inhibits hedonic feeding. The LS acts as a "brake system" within the brain's feeding-regulation network and represents a potential target for preventing and treating obesity.
A research team led by Prof. QIAN Youcun from the Shanghai Institute of Nutrition and Health of the Chinese Academy of Sciences identified a new member of the human IL‑17 receptor family, IL‑17REL, which plays a protective role in inflammatory bowel disease (IBD), and showed that genetic variants in IL17REL critically affect IBD.
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